A scarcity of uncomfortable side effects doesn’t imply the vaccine isn’t working, mentioned Dr. Paul Offit, a professor on the College of Pennsylvania and a member of the Meals and Drug Administration’s vaccine advisory panel. Dr. Offit famous that through the vaccine trials, a big variety of folks didn’t report uncomfortable side effects, and but the trials confirmed that about 95 p.c of individuals have been protected. “That proves you don’t must have uncomfortable side effects as a way to be protected,” he mentioned.
No one actually is aware of why some folks have loads of uncomfortable side effects and others have none. We do know that youthful folks mount stronger immune responses to vaccines than older folks, whose immune programs get weaker with age. Girls sometimes have stronger immune responses than males. However once more, these variations don’t imply that you simply aren’t protected if you happen to don’t really feel a lot after getting the shot.
Scientists nonetheless aren’t certain how efficient the vaccines are in folks whose immune programs could also be weakened from sure medical situations, comparable to most cancers remedies or H.I.V. an infection or as a result of they’re taking immune suppressing medication. However most consultants consider the vaccines nonetheless supply these sufferers some safety towards Covid-19.
The underside line is that although particular person immune responses can range, the information collected thus far present that each one three vaccines permitted in the USA — Pfizer-BioNTech, Moderna and Johnson & Johnson — are efficient towards extreme sickness and dying from Covid-19.
Q: I took Tylenol earlier than I had my Covid vaccine photographs and had little or no response to the photographs. Did I make a giant mistake?
You shouldn’t attempt to stave off discomfort by taking a ache reliever earlier than getting the shot. The priority is that premedicating with a ache reliever like acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), which might stop uncomfortable side effects like arm soreness in addition to fever or headache, may also blunt your physique’s immune response.
Whereas it’s attainable that taking a ache reliever earlier than your photographs may need dampened your physique’s immune response, vaccine consultants say you shouldn’t fear, and also you shouldn’t attempt to get a brand new spherical of substitute photographs. Research of different vaccines counsel that whereas premedicating can boring the physique’s immune response to a vaccine, your immune system can nonetheless mount a robust sufficient protection to battle an infection. A evaluate of research of greater than 5,000 youngsters in contrast antibody ranges in youngsters who took ache relievers earlier than and after vaccinations and people who didn’t. They discovered that ache relievers didn’t have a significant impression on immune response, and that youngsters in each teams generated sufficient ranges of antibodies after their photographs.
The excessive efficacy of all of the Covid vaccines means that even when taking Tylenol earlier than the shot did blunt your physique’s immune response, there’s some wiggle room, and you’re possible nonetheless effectively protected towards Covid-19. “It’s best to really feel reassured that you simply’ll have sufficient of an immune response that you simply’ll will likely be protected, particularly for vaccines which might be this good,” mentioned Dr. Offit.